9. Fabrazyme – $200,000 per year
Fabrazyme helps treat Fabry disease when it’s delivered intravenously every two weeks. The disease is an uncommon genetic disorder that prevents a certain type of fat from metabolizing, resulting in the disruption of a variety of biological systems.
The known symptoms include cloudy eyes, ringing in the ears, pain in the extremities and can result in heart attack, stroke and severe kidney problems.
About 1 in 40,000 to 60,000 men fall victim to the disease while women are much less likely to contract the ailment.
This medication is noted for a high rate of severe reactions, sometimes requiring taking other drugs to mitigate the negative side effects.